Spontaneous Coronary Artery Dissection in an Orthotopic Heart Transplant Recipient

Josephine Warren1, Caitlin Cheshire1, Sarah Gutman1,2

  • 1Department of Cardiology Alfred Hospital, Melbourne, Australia.

JACC. Case Reports
|August 8, 2022
PubMed

Insights

We report a rare case of acute myocardial infarction caused by spontaneous coronary artery dissection just two weeks after a heart transplant. This highlights a potential complication following orthotopic heart transplantation.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Cardiovascular Surgery

Background:

  • Orthotopic heart transplantation is a life-saving procedure for end-stage heart failure.
  • Spontaneous coronary artery dissection (SCAD) is a rare but serious condition affecting coronary arteries.
  • Post-transplant complications require vigilant monitoring and prompt diagnosis.

Observation:

  • A patient developed acute myocardial infarction (heart attack) symptoms.
  • The infarction was found to be secondary to spontaneous coronary artery dissection.
  • This event occurred two weeks after undergoing an orthotopic heart transplantation.

Findings:

  • The case demonstrates a novel association between SCAD and recent heart transplantation.
  • Early diagnosis of SCAD in post-transplant patients is crucial for management.
  • Coronary angiography confirmed SCAD as the cause of myocardial infarction.

Implications:

  • This case underscores the importance of considering SCAD in heart transplant recipients presenting with ischemic symptoms.
  • Further research may elucidate the specific mechanisms linking transplantation and SCAD.
  • Timely recognition and intervention can improve outcomes for these complex patients.

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