Related Experiment Video
Updated: Sep 2, 2025

A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
A Case Report of Accelerated Pulmonary Silicosis: Hazardous Exposure in Underrepresented Community Members
Sara Patino1, Guillermo Izquierdo-Pretel1
1Internal Medicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Abstract:
A 39-year-old undocumented male immigrant with occupational exposure to quartz, without significant medical history, presented with worsening cough, dyspnea, and weight loss for the past six months, with onset of symptoms starting two years ago. The patient was exposed to silicon dioxide for the past 10 years due to his occupation. Chest x-ray at the time of diagnosis reflected multifocal heterogeneous opacities; CT of the chest demonstrated eggshell calcifications and conglomerate opacities particularly involving the bilateral upper lobes. Transbronchial biopsy reflected non-necrotizing granulomatous inflammation. In the context of silica dust exposure, these findings suggest the diagnosis of accelerated silicosis. This case report seeks to bring attention to the potential increased risk of occupational diseases in the community members who have high exposure to environmental hazards.
More Related Videos
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Chronic Obstructive Pulmonary Disease-I: Introduction
Other Pulmonary Disorders
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

