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COVID-19 Vaccine Booster-Induced Dermatographism.

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COVID-19 vaccines are crucial, but some rare skin reactions can occur. This case report details a young man experiencing chronic severe dermatographism after a Moderna booster, highlighting the need for further investigation into vaccine-related cutaneous events.

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chronic spontaneous urticariacovid 19 vaccinecutaneous reactionsdermatographismmorbilliform drug eruption

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Area of Science:

  • Immunology
  • Dermatology
  • Vaccinology

Background:

  • The COVID-19 pandemic necessitated rapid vaccine development and deployment.
  • Adverse events following immunization (AEFIs) are monitored for all vaccines, including COVID-19 vaccines.
  • Cutaneous reactions are known but their incidence and severity post-COVID-19 vaccination require further study.

Observation:

  • This article presents a case of a young male patient.
  • The patient developed chronic severe dermatographism.
  • This reaction occurred after receiving a Moderna COVID-19 vaccine booster shot.

Findings:

  • Dermatographism is a skin condition characterized by wheal and flare reactions upon skin stroking.
  • The patient's dermatographism was severe and chronic following vaccination.
  • This represents an unusual and potentially underreported adverse event associated with COVID-19 vaccination.

Implications:

  • This case highlights a rare but significant cutaneous adverse event potentially linked to COVID-19 vaccines.
  • Further research is needed to understand the frequency and mechanisms of vaccine-induced dermatographism.
  • Clinicians should be aware of this potential side effect when managing patients post-vaccination.