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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
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Related Experiment Video

Updated: Sep 2, 2025

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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Braided composite stent for peripheral vascular applications.

Qingli Zheng1, Pengfei Dong2, Zhiqiang Li3

  • 1Institute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Nanotechnology Reviews
|August 8, 2022
PubMed
Summary
This summary is machine-generated.

The mechanical performance of braided composite stents (BCS) was analyzed. Nitinol wire diameter and braiding angle significantly impact radial strength and flexibility, guiding optimal stent design.

Keywords:
atherosclerosisbraided composite stentfinite element methodflexibilityradial strengthsurface coverage

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Area of Science:

  • Biomaterials Engineering
  • Medical Device Design
  • Computational Mechanics

Background:

  • Braided composite stents (BCS) offer a hybrid design combining nitinol wires and polyethylene terephthalate (PET) strips.
  • The mechanical properties of these novel stents require thorough investigation for clinical application.

Purpose of the Study:

  • To systematically investigate the influence of key design factors on the mechanical performance of BCS.
  • To provide guidance for optimizing BCS design to minimize complications.

Main Methods:

  • Computational modeling was employed to study five design factors: nitinol wire number, braiding angle, nitinol wire diameter, PET strip thickness, and PET strip stiffness.
  • Orthogonal experimental design was utilized for efficient quantitative analysis of factor sensitivity.

Main Results:

  • Nitinol wire diameter and braiding angle were identified as the most critical factors for mechanical performance.
  • Increased nitinol wire diameter enhanced radial strength but reduced flexibility.
  • A larger braiding angle improved both radial strength and flexibility, though its impact diminished under large deformation.

Conclusions:

  • The study elucidates the relationship between design parameters and mechanical behavior of BCS.
  • Nitinol wire diameter and braiding angle are key determinants of stent performance.
  • PET strip properties become more influential during large deformations, and PET strip count affects surface coverage, informing future stent optimization.