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Unusual presentation in amyloidosis

Ines Mahmoud1, Leila Rouached1, Meriem Chammakhi1

  • 1Department of Rheumatology Charles Nicolle Hospital Tunis Tunisia.

Clinical Case Reports
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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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Keywords:
amyloisarthropathybiopsymultiple myelomaspine