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Cardiovascular markers and COVID-19
El-Houcine Sebbar1,2, Mohammed Choukri1,2
1Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, PB 724, Oujda 60000, Morocco.
Materials Today. Proceedings
|August 8, 2022
Summary
Biomarkers like troponin and d-dimer indicate cardiac injury in COVID-19 patients. Elevated levels predict severe outcomes and mortality, highlighting their importance in disease management.
Area of Science:
- Cardiology
- Infectious Diseases
- Biomarkers
Background:
- COVID-19 presents with varied clinical profiles and incompletely understood pathogenesis.
- Cardiovascular complications are frequent, including acute cardiac injury, myocardial infarction, myocarditis, heart failure, and thromboembolism.
- Elevated cardiac biomarkers suggest myocardial damage as a key factor in severe COVID-19.
Purpose of the Study:
- To emphasize the predictive value of cardiac biomarkers for cardiovascular complications in COVID-19.
- To explore the role of these biomarkers in the disease's progression and patient outcomes.
Main Methods:
- Analysis of biomarker levels (BNP/NT-proBNP, troponin, d-dimer) in COVID-19 patients.
- Correlation of biomarker levels with clinical presentation and disease severity.
- Assessment of biomarker association with adverse cardiovascular events and mortality.
Main Results:
- Significant elevations in BNP/NT-proBNP, troponin, and d-dimer were observed in a substantial number of patients.
- Higher levels of these biomarkers correlated with increased risk of adverse outcomes, including mortality.
- Myocardial damage, indicated by these markers, appears to be a critical pathogenic mechanism.
Conclusions:
- Cardiac biomarkers are crucial for predicting cardiovascular complications in COVID-19.
- Monitoring these markers aids in risk stratification and understanding disease evolution.
- These biomarkers play a significant role in assessing the prognosis of COVID-19 patients.
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