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Related Experiment Video

Updated: Sep 2, 2025

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Monkeypox - An emerging pandemic.

Kunal M Ajmera¹, Lokesh Goyal², Trupti Pandit³

¹Department of Hospital Medicine, Sentara Northern Virginia Medical Center, Woodbridge, VA, USA.

|August 8, 2022

Summary

This summary is machine-generated.

Monkeypox is a growing zoonotic concern. Early detection, isolation, and vaccination for high-risk groups are key to managing this orthopoxvirus outbreak.

Keywords:

Antiviral treatment MSM Monkeypox Monkeypox rash Vaccination

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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Published on: April 10, 2009

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Last Updated: Sep 2, 2025

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Published on: April 10, 2009

Area of Science:

Virology
Epidemiology
Public Health

Background:

Monkeypox, a zoonotic disease caused by a virus in the Orthopoxviruses family, is experiencing a global surge.
Rising cases in the US and worldwide necessitate heightened awareness among healthcare professionals.

Observation:

New-onset fever, vesicular/pustular rash with central umbilication, and lymphadenopathy are key indicators.
The current outbreak disproportionately affects homosexual and gay populations, prompting further investigation into sexual transmission routes.

Findings:

Most monkeypox cases are self-limiting, requiring supportive care.
Vaccine prophylaxis is recommended by the CDC for immunocompromised individuals, pregnant patients, and children under eight.
Antivirals like tecovirimat (TPOXX) and brincidofovir, or intravenous vaccinia immune globulin (VIGIV), are options for severe cases.

Implications:

Prompt diagnosis and isolation are crucial to prevent secondary monkeypox transmission.
Targeted vaccination strategies are essential for vulnerable populations.
Further research into the role of sexual transmission is vital for effective public health interventions.