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    Area of Science:

    • Biomedical Engineering
    • Acoustics
    • Implantable Devices

    Background:

    • Millimeter-scale implants utilize ultrasound (US) for deep-tissue applications like neural interfacing.
    • Existing US-powered implants exhibit high sensitivity to misalignment with external transducers.

    Purpose of the Study:

    • To design a phased array US system for improved power and communication with millimeter-scale implants.
    • To enhance tolerance to misalignment and enable simultaneous operation of multiple implants.

    Main Methods:

    • Design and analysis of a custom planar phased array US system for 3-D focusing.
    • Simulation of array element pitch to maximize power transfer within FDA limits.
    • Implementation and comparison of Time Reversal (TR) beamforming in active drive and pulse-echo modes.

    Main Results:

    • Demonstrated a phased array US system capable of steering and focusing power in 3-D.
    • Time Reversal beamforming proved robust in scattering media and efficient for energy transfer.
    • Simultaneous power delivery to multiple implants was successfully demonstrated.

    Conclusions:

    • Phased array ultrasonic beamforming significantly improves misalignment tolerance for implantable devices.
    • Time Reversal offers a computationally efficient and robust method for ultrasonic beamforming in complex environments.
    • The developed system supports simultaneous power delivery to multiple implants, advancing deep-tissue applications.