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Soft Tissue Leiomyosarcoma With Microsatellite Instability, High Tumor Mutational Burden, and Programmed Death

Timothy Kwang Yong Tay1, Joe Poh Sheng Yeong1,2, Eileen Xueqin Chen3

  • 1Department of Anatomical Pathology, Singapore General Hospital, Singapore.

JCO Precision Oncology
|August 8, 2022
PubMed
Abstract

No abstract available in PubMed .

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...