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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Related Experiment Video

Updated: Sep 2, 2025

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PREPARE trial: a protocol for a multicentre randomised trial of frailty-focused preoperative exercise to decrease

Daniel I McIsaac1, Dean A Fergusson2, Rachel Khadaroo3

  • 1Anesthesiology and Pain Medicine, Ottawa Hospital Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada dmcisaac@toh.ca.

BMJ Open
|August 8, 2022
PubMed
Summary
This summary is machine-generated.

This study investigates home-based prehabilitation for older adults with frailty undergoing major surgery. Multimodal prehabilitation aims to reduce postoperative disability and complications, improving surgical outcomes for this vulnerable population.

Keywords:
clinical trialsgeriatric medicinesurgery

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Area of Science:

  • Geriatric Medicine
  • Surgical Outcomes Research
  • Rehabilitation Science

Background:

  • Frailty is a significant predictor of adverse outcomes following major surgery in older adults.
  • Prehabilitation interventions, targeting physical and physiological deficits, show promise in mitigating these risks.
  • Optimizing pre-operative care for frail individuals is crucial for improving surgical recovery and patient well-being.

Purpose of the Study:

  • To evaluate the efficacy of a home-based multimodal prehabilitation program in reducing patient-reported disability and postoperative complications.
  • To assess the impact of prehabilitation on functional recovery, quality of life, and resource utilization in older surgical patients with frailty.
  • To provide evidence for the implementation of accessible prehabilitation strategies in geriatric surgical care.

Main Methods:

  • A multicentre, randomized controlled trial involving 750 participants aged over 60 with frailty (Clinical Frailty Scale ≥4).
  • Intervention group receives >3 weeks of home-based prehabilitation (exercise and nutritional support) versus standard care.
  • Primary outcomes include in-hospital complications and patient-reported disability at 30 days post-surgery; long-term follow-up to 1 year.

Main Results:

  • (Study currently in progress; results pending dissemination)

Conclusions:

  • (Study currently in progress; conclusions pending dissemination)