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1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains

Jiewei Jiang1, Pei-Liang Zhao1, Logan H Sigua2

  • 1Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA.

Archiv Der Pharmazie
|August 8, 2022
PubMed

Keywords:
AlphaScreenBET selectivityBROMOscanX-raybromodomain and extra-terminal (BET) proteins

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