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Related Experiment Video

Updated: Sep 2, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

Progress in COVID research and developments during pandemic.

Sudheesh K Shukla^1,2, Santanu Patra^1,2, Trupti R Das³

¹Institute of Advanced Materials IAAM Gammalkilsvägen 18 Ulrika 59053 Sweden.

View (Beijing, China)

|August 9, 2022

Summary

Accurate COVID-19 diagnosis is crucial for reducing infections and deaths. This review explores current diagnostic methods, highlighting sensor and digital medicine technologies for accessible, mass-level screening and effective public health management.

Keywords:

COVID science and technology COVID‐19 diagnosis artificial intelligence corona virus pandemic years respiratory tract infection serological test

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Last Updated: Sep 2, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

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Area of Science:

Infectious Diseases
Public Health
Biotechnology

Background:

The COVID-19 pandemic necessitates rapid and accurate diagnostic tools.
Challenges include understanding host susceptibility, clinical features, and asymptomatic infections.
Effective medication and immunization are still limited, increasing the need for precise diagnostics.

Purpose of the Study:

To systematically review current screening and diagnostic approaches for COVID-19.
To identify advancements in diagnostic technologies for mass-level application.
To propose a healthcare model for effective prognosis and public health management.

Main Methods:

Systematic review of existing COVID-19 diagnostic strategies.
Analysis of emerging technologies like sensor and digital medicine.
Evaluation of diagnostic tools based on candidate biomarkers.

Main Results:

Current diagnostic approaches face challenges due to pathogen adaptability and new variants.
Sensor and digital medicine technologies offer potential for accurate, affordable, mass-level COVID-19 diagnosis.
High specificity and cost-effectiveness are key for public health management.

Conclusions:

Standardized diagnostic approaches are urgently needed for COVID-19.
Technological advancements in diagnostics are vital for pandemic control.
A multidisciplinary approach integrating research, policy, and technology is essential for improved public health outcomes.