Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

21.4K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
21.4K
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

463
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
463
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

635
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
635
Properties of Organometallic Compounds01:23

Properties of Organometallic Compounds

1.1K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
1.1K
Complexometric Titration: Ligands00:43

Complexometric Titration: Ligands

1.1K
Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
1.1K
Formation of Complex Ions03:45

Formation of Complex Ions

23.9K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
23.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Macrocyclic stibine-bridged [1.1.1] and [1.1.1.1]ferrocenophanes.

Chemical communications (Cambridge, England)·2026
Same author

Visible-light-induced chlorine photoelimination from acridinium-phosphine gold(iii) complexes.

Chemical science·2026
Same author

Redox-Controlled Chalcogen Bonding as a Modulator of ZnCl<sub>2</sub> Chelation and Transport.

Journal of the American Chemical Society·2026
Same author

Fluoride ion chelation <i>via</i> pnictogen bonding using a distibora[1.1]ferrocenophane.

Chemical communications (Cambridge, England)·2026
Same author

Flash Communication: Properties and Applications of a Pentavalent Bromoantimony Lewis Acid.

Organometallics·2026
Same author

Pnictogen-Bonding Catalysis: Copolymerization of CO<sub>2</sub> and Epoxides on Antimony(V) Platforms.

ACS catalysis·2025

Related Experiment Video

Updated: Sep 2, 2025

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold
05:28

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold

Published on: February 10, 2023

1.7K

Augmenting metallobasicity to modulate gold hydrogen bonding.

Logan T Maltz1, Lewis C Wilkins1, François P Gabbaï1

  • 1Department of Chemistry, Texas A&M University, College Station, TX 77843, USA. francois@tamu.edu.

Chemical Communications (Cambridge, England)
|August 9, 2022
PubMed
Summary

Researchers synthesized gold carbinol compounds to study intramolecular hydrogen bonds. Stronger gold-ligand bonds increased hydrogen bond strength, confirmed by experiments and calculations.

More Related Videos

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions
08:21

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions

Published on: February 5, 2016

22.2K
Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
08:53

Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids

Published on: March 21, 2025

858

Related Experiment Videos

Last Updated: Sep 2, 2025

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold
05:28

Versatile Technique to Produce a Hierarchical Design in Nanoporous Gold

Published on: February 10, 2023

1.7K
A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions
08:21

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions

Published on: February 5, 2016

22.2K
Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
08:53

Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids

Published on: March 21, 2025

858

Area of Science:

  • Organometallic Chemistry
  • Supramolecular Chemistry
  • Hydrogen Bonding

Background:

  • Intramolecular hydrogen bonding plays a crucial role in molecular structure and reactivity.
  • Gold complexes offer unique electronic properties for investigating non-covalent interactions.

Purpose of the Study:

  • To synthesize and characterize novel phosphine gold carbinol species.
  • To investigate the influence of gold metallobasicity on intramolecular Au⋯H-O hydrogen bond strength.

Main Methods:

  • Synthesis of two phosphine gold carbinol complexes with varying gold ligand environments.
  • Experimental analysis including spectroscopy (NMR, IR) and X-ray crystallography.
  • Computational studies (e.g., DFT calculations) to probe electronic structure and bonding interactions.

Main Results:

  • Successful synthesis and full characterization of the target gold carbinol complexes.
  • Demonstrated a direct correlation between increased gold metallobasicity (via ligand substitution from chloride to phenyl) and enhanced Au⋯H-O hydrogen bond strength.
  • Experimental and computational data confirmed the strengthening of the intramolecular hydrogen bond.

Conclusions:

  • Ligand modification of gold complexes can effectively tune the strength of intramolecular hydrogen bonds.
  • Metallobasicity is a key factor in modulating non-covalent interactions involving gold centers.
  • These findings provide insights into the design of gold complexes for applications in catalysis and materials science.