Related Experiment Video
Updated: Sep 2, 2025
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
Clinical Practice Guideline—Acute and Chronic Pancreatitis
Georg Beyer1, Albrecht Hoffmeister, Pia Lorenz
1Department of Internal Medicine II, LMU Hospital, Munich, Germany; Department of Gastroenterology and Rheumatology, Leipzig University Hospital, Leibzig, Germany; German Society of Gastroenterology, Digestive and Metabolic Disease (DGVS), Berlin, Germany; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany; LMU Hospital, Munich, Germany.
Acute pancreatitis (AP) is a common gastrointestinal diagnosis. Early feeding and Ringer's lactate fluid resuscitation significantly reduce complications and mortality in AP patients.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Acute pancreatitis (AP) is a frequent non-malignant diagnosis in gastroenterology.
- Incidence in Germany is increasing, with 24 per 100,000 hospitalized for chronic pancreatitis in 2017.
Approach:
- Systematic literature search for original articles, meta-analyses, and guidelines (1960-2018).
- Focus on diagnosis and treatment of acute pancreatitis.
Key Points:
- Gallstones and alcohol abuse cause 30-50% of AP cases.
- Diagnosis requires two of: typical pain, elevated serum lipase, or imaging findings.
- Early feeding reduces infected necrosis, organ failure, and death (OR 0.44).
- Ringer's lactate is preferred for fluid resuscitation; opiates for pain management.
Conclusions:
- The German clinical practice guideline incorporates recent advancements in AP diagnosis and treatment.
- Primary care physicians and gastroenterologists manage long-term care for uncomplicated pancreatitis.
Related Concept Videos
01:29Chronic Pancreatitis II: Collaborative Care
Assessment:
01:30Acute Pancreatitis II: Clinical Manifestations and Management
01:24Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
01:27Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
01:26Endoscopic Procedures V: ERCP
Patient...
01:28Chronic Kidney Disease III: Interprofessional Care