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Correlation of Multidetector Computed Tomography Peripheral Angiography with Color Duplex Sonography in Peripheral
Rameshwor Devkota1, Birendra Raj Joshi2, Kamal Subedi2
1Department of Radiology, Rapti Provincial Hospital, Dang, Nepal.
Insights
Duplex imaging is a safe, cost-effective, and reliable method for evaluating peripheral arterial disease. It offers high accuracy, making it a valuable diagnostic tool for this increasingly common condition.
Area of Science:
- Vascular Medicine
- Diagnostic Imaging
- Medical Technology
Background:
- Peripheral arterial disease (PAD) prevalence increases with global population aging.
- Conventional imaging modalities like arteriography, CT angiography, and MR angiography have limitations including invasiveness, cost, and contraindications.
- Duplex imaging presents a cost-effective, widely available, and safe alternative, even for patients with renal impairment or contrast allergies.
Purpose of the Study:
- To evaluate the diagnostic performance of duplex imaging for peripheral arterial disease.
- To compare duplex imaging findings with multi-detector computed tomography angiography (MDCT) as the gold standard.
Main Methods:
- A prospective cross-sectional study included 114 patients evaluated between November 2015 and October 2016.
- Lower limb arteries were divided into 10 segments for comparison between Doppler ultrasound and MDCT.
- Data analysis involved comparing stenosis and occlusion findings, with MDCT as the gold standard.
Main Results:
- Duplex imaging demonstrated high diagnostic accuracy with sensitivity (94.94%), specificity (98.54%), and overall accuracy (97.54%).
- A positive correlation was found between velocity ratio and the degree of partial occlusion (r=0.918 for the right lower limb, r=0.895 for the left).
- Overestimation of complete stenosis occurred in Doppler assessment for partial stenosis identified by MDCT in 22 segments.
Conclusions:
- Duplex imaging is a safe, cost-effective, and reliable method for evaluating peripheral arterial diseases.
- The study confirms the high accuracy and utility of duplex imaging in PAD diagnosis.
Background:
With aging of the global population peripheral arterial disease is increasingly common. Arteriography, computed tomography angiography and magnetic resonance angiography are common modalities used for evaluation of peripheral arterial disease. However, they have limitations of being invasive, costly, limited availability or contraindicated in patients with renal impairment or contrast allergy. Duplex imaging, a method of evaluation of peripheral arterial disease is cost effective, widely available and safe even in patients with renal impairment and contrast allergy.
Methods:
A prospective cross sectional descriptive study involving 114 patients was conducted from November 2015 to October 2016. The patients were evaluated by Doppler ultrasound following multi-detector computed angiography in Department of Radiology, Tribhuvan University Teaching Hospital. The lower limb arteries were divided into 10 segments and stenosis or occlusion of each segment in Computed Tomography angiography were compared with findings in Doppler, Computed Tomography angiography being considered the gold standard. Data was collected in predesigned proforma in Microsoft Excel spread sheet.
Results:
Duplex imaging showed sensitivity 94.94%, specificity 98.54%, accuracy 97.54%, positive predictive value 96.15 % and negative predictive value 98.06 %. In assessment of 22 segments, partial stenosis seen in Computed Tomography angiography was overestimated as complete stenosis in Doppler. There was significant positive correlation of velocity ratio with degree of partial occlusion (r=0.918 for right lower limb and r=0.895 for left lower limb, p <0.01).
Conclusions:
Duplex imaging is safe cost effective and reliable method of evaluation of patients with peripheral arterial diseases.
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