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Published on: June 29, 2014
Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based
Ryan Kenneally1, Quentin Lawrence1, Ella Brydon1
1Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA, 94720, USA.
Abstract:
SARS-CoV-2 spread rapidly, causing millions of deaths across the globe. As a result, demand for medical supplies and personal protective equipment (PPE) surged and supplies dwindled. Separate entirely, hospital-acquired infections have become commonplace and challenging to treat. To explore the potential of novel sterilization techniques, this study evaluated the disinfection efficacy of Fathhome's ozone-based, dry-sanitizing device by dose and time response. Inactivation of human pathogens was tested on non-porous (plastic) surfaces. 95.42-100% inactivation was observed across all types of vegetative microorganisms and 27.36% inactivation of bacterial endospores tested, with no residual ozone detectable after completion. These results strongly support the hypothesis that Fathhome's commercial implementation of gas-based disinfection is suitable for rapid decontamination of a wide variety of pathogens on PPE and other industrially relevant materials.
Insights
This study shows ozone gas effectively disinfects medical supplies and personal protective equipment (PPE), inactivating over 95% of common pathogens without harmful residue.
Area of Science:
- Microbiology
- Environmental Science
- Biomedical Engineering
Background:
- The rapid spread of SARS-CoV-2 highlighted critical shortages of personal protective equipment (PPE) and the persistent challenge of hospital-acquired infections.
- Effective and rapid sterilization methods are crucial for managing infectious disease outbreaks and maintaining healthcare safety.
Purpose of the Study:
- To evaluate the disinfection efficacy of a novel ozone-based, dry-sanitizing device for decontaminating non-porous surfaces.
- To determine the dose and time response of the ozone device against various human pathogens.
Main Methods:
- Testing the inactivation of vegetative microorganisms and bacterial endospores on plastic surfaces using Fathhome's ozone device.
- Assessing pathogen inactivation rates based on varying ozone doses and exposure times.
- Monitoring for residual ozone after the disinfection process.
Main Results:
- Achieved 95.42-100% inactivation of vegetative microorganisms across tested conditions.
- Demonstrated 27.36% inactivation of bacterial endospores.
- Confirmed no detectable residual ozone post-treatment.
Conclusions:
- The ozone-based dry-sanitizing device shows significant potential for rapid decontamination of PPE and other materials.
- This technology offers a viable solution for addressing pathogen control in healthcare and industrial settings.
- The method is effective against a broad spectrum of microorganisms with no harmful byproducts.
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