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Updated: Sep 2, 2025

Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink
Published on: April 21, 2016
Correction: Dual crosslinking hydrogels with tunable injectability and stability for bone repair
Wenlin Chu1, Xiang Ke1, Zhiyun Dong1
1College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China. luojuncd@scu.edu.cn.
This correction clarifies details in a study on dual crosslinking hydrogels for bone repair. The research focused on optimizing hydrogel properties for enhanced injectability and stability in bone regeneration applications.
Area of Science:
- Materials Science
- Biomedical Engineering
- Polymer Chemistry
Context:
- Bone defects present a significant clinical challenge requiring advanced regenerative strategies.
- Hydrogels offer promising biomaterials for bone tissue engineering due to their biocompatibility and tunable properties.
- Achieving both injectability for minimally invasive delivery and long-term stability in vivo remains a critical hurdle for bone repair hydrogels.
Purpose:
- To correct and clarify specific aspects of the original publication concerning dual crosslinking hydrogels.
- To ensure accurate representation of the methodology and findings related to hydrogel formulation and characterization.
- To provide a precise understanding of the hydrogel system's potential for bone regeneration.
Summary:
- The correction addresses specific experimental details and data interpretations within the original study on dual crosslinking hydrogels.
- It refines the understanding of how dual crosslinking influences hydrogel injectability, mechanical stability, and degradation profiles.
- The revised information enhances the clarity on the hydrogel's performance in supporting osteogenic differentiation and bone matrix deposition.
Impact:
- Ensures the scientific community has access to accurate information for the development of advanced bone void fillers.
- Facilitates reliable translation of dual crosslinking hydrogel technology towards clinical applications in orthopedic surgery.
- Provides a corrected foundation for future research in biomaterials for skeletal tissue regeneration.
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