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The lung fibroblast as "soil fertilizer" in breast cancer metastasis
Julia M Houthuijzen1, Karin E de Visser2
1Division of Molecular Pathology, Oncode Institute, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.
Immunity
|August 10, 2022
Abstract:
Fibroblasts strongly impact tumor progression, but whether they prime the pre-metastatic niche is poorly understood. In this issue of Immunity, Gong and Li et al. identify lung-specific immunosuppressive fibroblasts, which are hijacked by breast cancer cells to facilitate metastasis.

