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Another physician's office analyzer: the Abbott "Vision" evaluated.

J M Hicks, M Iosefsohn

    Clinical Chemistry
    |June 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

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    The Abbott Vision system shows good precision for physician office lab testing. However, interference from hemolysis and bilirubin, and bias in certain analytes, require careful consideration for accurate clinical use.

    Area of Science:

    • Clinical Chemistry
    • Laboratory Medicine
    • Point-of-Care Testing

    Background:

    • Physician office laboratories (POLs) require reliable diagnostic tools.
    • The Abbott Vision system is a potential option for POLs.
    • Performance data is needed to validate its use in this setting.

    Purpose of the Study:

    • To evaluate the Abbott Vision system for POL suitability.
    • To compare its analytical performance against established methods.
    • To identify potential interferences and assess operator variability.

    Main Methods:

    • Analyzed multiple analytes (e.g., glucose, cholesterol) using the Abbott Vision system.
    • Compared results with Kodak Ektachem 400/700 systems.
    • Assessed linearity, precision, and interference from hemolysis and bilirubin.

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  • Evaluated operator skill impact.

    • Main Results:

    • Good standard curve linearity and acceptable precision (CVs 0.9%-7.3%) were observed for most analytes.
    • Bias noted for blood urea nitrogen and alkaline phosphatase.
    • Hemolysis and bilirubin caused significant interference with several analytes.
    • Calibration stability was confirmed for one month.

    Conclusions:

    • The Abbott Vision system demonstrates acceptable analytical performance for many common chemistries in a POL setting.
    • Interference from hemolysis and bilirubin, and bias in specific analytes, necessitate careful interpretation and procedural controls.
    • Operator variability did not significantly impede performance.