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Inhibitors of Viral Protein Synthesis

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...

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Related Experiment Video

Updated: Jun 16, 2026

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function

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Published on: October 15, 2013

Improving interferon-γ release assay interpretation: are IP-10 and MIG the solution?

Francesca Saluzzo^1,2, Claudia M Denkinger^3,4, Daniela M Cirillo⁵

¹IRCCS San Raffaele Scientific Institute, Milan, Italy.

The European Respiratory Journal

|August 10, 2022

Summary

No abstract available in PubMed .

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