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New Frontiers in Placenta Tissue Imaging.

Christopher D Nguyen1, Ana Correia-Branco2,3, Nimish Adhikari4

  • 1Tufts University, Department of Biomedical Engineering, 4 Colby St, Medford, MA 02155.

EMJ. Radiology
|August 11, 2022
PubMed
Summary

Advanced imaging techniques offer new ways to understand placental health and disorders like preeclampsia and intrauterine growth restriction (IUGR). These methods improve diagnosis and maternal-fetal health monitoring.

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Area of Science:

  • Obstetrics and Gynecology
  • Medical Imaging
  • Fetal Development

Background:

  • The placenta is vital for fetal support, mediating nutrient, oxygen, and waste exchange.
  • Impaired placental health is linked to adverse pregnancy outcomes (preeclampsia, IUGR, preterm birth) and future maternal cardiovascular disease.
  • Current placental imaging methods may be limited by time, cost, or invasiveness.

Purpose of the Study:

  • To review advanced imaging modalities for placental structural, vascular, and metabolic analysis.
  • To highlight emerging frontiers in placental image analysis for preclinical and clinical applications.
  • To improve noninvasive assessment of placental function for enhanced maternal-fetal health monitoring.

Main Methods:

  • Discussion of advanced imaging modalities beyond traditional ultrasound (US).
  • Focus on applications in structural, vascular, and metabolic placental analysis.
  • Exploration of emerging image analysis research in placental imaging.

Main Results:

  • Advanced imaging provides insightful data on placental tissue structure.
  • These techniques can offer detailed insights into placental vascular and metabolic functions.
  • Emerging image analysis frontiers promise improved diagnostic capabilities.

Conclusions:

  • Noninvasive placental imaging and analysis are crucial for advancing obstetric clinical reasoning.
  • Improved imaging tools can enhance the interpretation of maternal and fetal health trajectories.
  • Further research in advanced imaging and analysis is needed to address incompletely understood placental disorders.