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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
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Related Experiment Video

Updated: Sep 2, 2025

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
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Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements.

Yongkun Sun1, Wen Zhang1, Xinyu Bi2

  • 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Liver Cancer
|August 11, 2022
PubMed
Summary

New guidelines address advanced hepatocellular carcinoma (HCC) treatment in China. This review focuses on novel molecular targeted therapies and immune checkpoint inhibitors for improved patient outcomes.

Keywords:
Chinese interdisciplinary expertsConsensusHepatocellular carcinomaMolecular targeted therapy

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Area of Science:

  • Hepatology
  • Oncology
  • Pharmacology

Background:

  • Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality globally and in China.
  • Advanced stage HCC is frequently diagnosed, posing significant treatment challenges.

Purpose of the Study:

  • To establish Chinese guidelines for novel molecular targeted therapies in advanced HCC.
  • To provide evidence-based recommendations for the use of new drugs in HCC management.

Main Methods:

  • An interdisciplinary panel reviewed existing literature on advanced HCC treatments.
  • Consensus statements were developed based on published data and expert opinion.

Main Results:

  • The guidelines cover appropriate use, dosing, and combination therapies for new molecular targeted drugs.
  • Recommendations include adverse event management, efficacy evaluation, and treatment prediction.

Conclusions:

  • The developed guidelines aim to standardize and improve the systemic treatment of advanced HCC in China.
  • This initiative provides a crucial overview of molecular targeted therapies for healthcare professionals treating HCC.