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Curbing antimicrobial resistance in post-COVID Africa: Challenges, actions and recommendations
Deborah Oluwaseun Shomuyiwa1, Don Eliseo Lucero-Prisno2,3,4, Emery Manirambona5
1Faculty of Pharmacy University of Lagos Lagos Nigeria.
Background:
Antimicrobial self-medication and use have significantly increased in the COVID-19 era-increasing antibiotic consumption and resulting in a high prevalence of antimicrobial resistance in Africa (AMR). We conducted a narrative review to investigate challenges associated with curbing AMR in a post-COVID-19 setting in Africa, suggesting practical measures applicable for policy-informed implementation.
Method:
A narrative review was performed to pinpoint AMR challenges and actions on the African continent. A comprehensive search was conducted in the scientific databases that include PubMed, PubMed Central and Google Scholar using predetermined search terms.
Results:
The emergence of the COVID-19 outbreak has added to the challenges of tackling AMR on the continent, which has jeopardized AMR interventions' hard-won gains. Identified challenges have been Health systems disruption, Irrational Antimicrobial Use, Weak Antimicrobials Regulatory Ecosystem, Inefficient Population Infection Prevention, and Control Practices, Inadequate access to Health Services and data challenge on AMR surveillance.
Conclusion:
The COVID-19 pandemic fueled AMR in Africa. There is a need for AMR control post-COVID, such as measures for ongoing antimicrobial stewardship and good infection control practices. Further, curbing AMR requires rigorous regulatory enforcement and efficient AMR Surveillance. There should be a body to raise AMR awareness among the population. Research, Innovation and Technology could play an essential role supported by capacity building and global partnership.
Insights
The COVID-19 pandemic exacerbated antimicrobial resistance (AMR) in Africa, increasing antibiotic use. Post-COVID-19 strategies must address health system challenges and strengthen antimicrobial stewardship and surveillance to curb AMR.
Area of Science:
- Public Health
- Infectious Diseases
- Global Health
Background:
- Antimicrobial self-medication and use surged during the COVID-19 pandemic.
- This led to increased antibiotic consumption and a high prevalence of antimicrobial resistance (AMR) in Africa.
- The pandemic has jeopardized previous AMR intervention gains on the continent.
Purpose of the Study:
- To investigate challenges associated with curbing AMR in Africa post-COVID-19.
- To suggest practical, policy-informed measures for AMR control.
Main Methods:
- A narrative review was conducted.
- A comprehensive literature search was performed in PubMed, PubMed Central, and Google Scholar.
Main Results:
- Key challenges identified include health system disruption, irrational antimicrobial use, weak regulatory ecosystems, inefficient infection prevention and control, inadequate healthcare access, and poor AMR surveillance data.
- The COVID-19 outbreak significantly worsened the AMR situation in Africa.
Conclusions:
- Effective AMR control post-COVID-19 requires ongoing antimicrobial stewardship and robust infection control practices.
- Rigorous regulatory enforcement, efficient AMR surveillance, public awareness campaigns, and investment in research, innovation, and technology are crucial.
- Capacity building and global partnerships are essential for sustained AMR efforts.
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