Electrooculographic findings in progressive supranuclear palsy

Progressive supranuclear palsy is a heterogeneous system degeneration. We studied three patients by means of electrooculography. There were severe disturbances in saccadic and smooth pursuit eye movements, and optokinetic nystagmus in both vertical and horizontal planes. Caloric reactions were absent in all patients. The absence of vestibular reflex responses in contrast to the normal results in doll's head manoeuvre seems contradictory and is discussed. From the results in our patients it is concluded that E.O.G. is an essential contribution in proving a multiple system pathology.