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[Vesicorenal reflux and kidney transplantation]
Helvetica Chirurgica Acta
|July 1, 1978
Summary
Vesicoureteral reflux (VUR) affects 30% of adult end-stage renal disease patients. This study found VUR is rarely the sole cause of renal insufficiency, often linked to chronic pyelonephritis or other congenital anomalies.
Area of Science:
- Nephrology
- Urology
- Pediatric Urology
Context:
- End-stage renal disease (ESRD) affects a significant adult population.
- Vesicoureteral reflux (VUR) is a known risk factor for renal damage.
- The prevalence and etiological role of VUR in adult ESRD require further elucidation.
Purpose:
- To determine the prevalence of VUR in adult patients with ESRD.
- To investigate the underlying causes of renal insufficiency in these patients.
- To assess the etiological significance of VUR in the development of ESRD.
Summary:
- A study of 85 adult ESRD patients revealed that 25 (30%) had VUR.
- Renal insufficiency was attributed to kidney disease alone in 15 patients, chronic pyelonephritis in 8, and megaloureter-megalocystis syndrome in 2.
- Uncomplicated, sterile VUR was not identified as a cause of renal insufficiency in the latter two groups, suggesting it is a rare etiological factor.
Impact:
- Highlights the significant prevalence of VUR in adult ESRD patients.
- Underscores the importance of considering VUR in the differential diagnosis of renal insufficiency.
- Suggests that VUR as an isolated cause of ESRD is uncommon, often coexisting with other urinary tract pathologies.