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Updated: Sep 1, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Thyroid, Diet, and Alternative Approaches.

Dana Larsen1, Sargun Singh2, Maria Brito1

  • 1Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

The Journal of Clinical Endocrinology and Metabolism
|August 11, 2022
PubMed
Summary

Many popular dietary and alternative therapies for thyroid disease lack proven benefits. Physicians should educate patients on the limited evidence and potential harms of these approaches for thyroid disorder management.

Keywords:
ashwagandhacomplementary medicineiodinelifestyle interventionsnaltrexone

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Area of Science:

  • Endocrinology
  • Nutritional Science
  • Integrative Medicine

Background:

  • Growing patient interest in complementary and alternative medicine (CAM) for managing thyroid disorders.
  • Need to critically evaluate the evidence supporting popular dietary and alternative therapies.
  • Physicians require evidence-based guidance to advise patients on these approaches.

Purpose of the Study:

  • To review the scientific evidence for vitamins, minerals, and elimination diets used by patients for thyroid disease.
  • To assess the efficacy and safety of commonly used alternative therapies for thyroid disorders.
  • To provide clinicians with an evidence-based summary for patient counseling.

Main Methods:

  • Systematic review of literature on dietary interventions and supplements for thyroid disorders.
  • Analysis of studies on iodine, selenium, zinc, vitamin B12, naltrexone, ashwagandha, gluten, dairy, cruciferous vegetables, and soy.
  • Evaluation of evidence quality and clinical significance.

Main Results:

  • Iodine supplementation is crucial for prevention but harmful in excess. Selenium and zinc show benefit in specific populations.
  • Limited evidence supports vitamin B12, naltrexone, or ashwagandha for thyroid disorders.
  • Gluten/dairy avoidance benefits only those with sensitivities; cruciferous vegetables/soy have minimal proven benefit.

Conclusions:

  • Many popular alternative and dietary therapies for thyroid disease lack robust scientific evidence.
  • Physicians must educate patients on the limited benefits, potential harms, and lack of data for many CAM approaches.
  • Evidence-based patient counseling is essential for informed decision-making in thyroid disorder management.