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North East India medicinal plants database (NEI-MPDB)
Kikrusenuo Kiewhuo1, Dipshikha Gogoi2, Hridoy Jyoti Mahanta1
1Advanced Computation and Data Sciences Division, CSIR-North East Institute of Science and Technology, Jorhat, 785 006, Assam, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201 002, Uttar Pradesh, India.
This study developed a comprehensive database of medicinal plants from North East India, analyzing their phytochemicals. This resource aids drug discovery by detailing therapeutic potential and aiding pharmaceutical development.
Area of Science:
- Ethnobotany
- Pharmacology
- Bioinformatics
Background:
- North East India is a global biodiversity hotspot with rich traditional knowledge of medicinal plants.
- Medicinal plants from this region are a valuable source of natural products and phytochemicals for the pharmaceutical industry.
Purpose of the Study:
- To create a comprehensive database of medicinal plants from North East India.
- To perform quantitative analysis of phytochemicals for enhanced understanding of therapeutic indications.
- To facilitate drug discovery and development.
Main Methods:
- Compiled a database of 561 unique medicinal plants and 9225 phytochemicals.
- Analyzed physicochemical properties of phytochemicals using Python scripts.
- Assessed ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) properties using open-access servers.
Main Results:
- Established the North East India Medicinal Plant Database (NEI-MPDB) with extensive phytochemical data.
- Quantitative analysis provides insights into therapeutic potential.
- Data facilitates connection between research groups and pharmaceutical industries.
Conclusions:
- The NEI-MPDB serves as a valuable resource for researchers and the pharmaceutical industry.
- The database can accelerate drug discovery and development by leveraging traditional knowledge and modern analysis.
- Facilitates the translation of ethnobotanical information into economic value.
