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Related Experiment Video

Updated: Sep 1, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
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A PDMS-based microneedle array electrode for long-term ECG recording.

Renxin Wang1,2, Jianxin Bai1, Xiaohang Zhu1

  • 1State Key Laboratory of Dynamic Testing Technology, North University of China, Taiyuan, 030051, China.

Biomedical Microdevices
|August 11, 2022
PubMed
Summary
This summary is machine-generated.

Flexible microneedle array electrodes (FMAE) offer a stable solution for long-term electrocardiogram (ECG) monitoring. These novel dry electrodes overcome the limitations of traditional wet electrodes, providing reliable bioelectrical signals without conductive gel.

Keywords:
ECGElectrode–skin interface impedanceFlexible dry electrodeMicroneedle arrayPDMS

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Wearable Technology

Background:

  • Traditional Ag/AgCl wet electrodes with conductive gel reduce short-term electrode-skin interface impedance (EII) for electrocardiogram (ECG) signal acquisition.
  • The inflexibility and instability of wet electrodes limit their use in long-term monitoring for intelligent wearable devices.
  • Dry electrodes offer a solution to the drying-out problem associated with conductive gels in wearable applications.

Purpose of the Study:

  • To develop a flexible microneedle array electrode (FMAE) for reliable, long-term ECG monitoring.
  • To evaluate the performance of FMAE compared to traditional electrodes in terms of impedance and signal quality.

Main Methods:

  • Fabrication of a flexible microneedle array electrode (FMAE) using a polydimethylsiloxane (PDMS) substrate.
  • The fabrication process involved silicon molding, dual PDMS shape-transferring, and encapsulation, ensuring low cost, repeatability, and biocompatibility.
  • Performance evaluation through impedance testing and long-term ECG monitoring in resting and jogging states.

Main Results:

  • FMAE demonstrated lower and more stable electrode-skin interface impedance (EII) compared to other tested electrodes.
  • Long-term ECG tests confirmed that FMAE can acquire durable, stable, and reliable bioelectrical signals.
  • The microneedle design effectively penetrates the stratum corneum (SC) to obtain high-quality signals.

Conclusions:

  • The developed FMAE is a promising technology for long-term, high-quality ECG monitoring.
  • FMAE overcomes the limitations of traditional wet electrodes, offering a flexible and stable alternative for wearable health devices.