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Related Concept Videos

Electroconvulsive Therapy01:30

Electroconvulsive Therapy

136
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
136

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Related Experiment Video

Updated: Sep 1, 2025

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
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Ride the Wave: Continuous Electroencephalography is Indicated in the Management of Traumatic Brain Injury.

Allie Eickholtz1, Shan Abbas2, Elysia James3

  • 124317Spectrum Health, Butterworth Hospital, General Surgery Residency, Grand Rapids, MI, USA.

Clinical EEG and Neuroscience
|August 12, 2022
PubMed
Summary

Continuous EEG (cEEG) monitoring detected seizures or high-risk patterns in 35% of traumatic brain injury (TBI) patients. Over half of these seizures would have been missed without cEEG, highlighting its importance for TBI patient care.

Keywords:
continuous EEGepilepsyseizuressubclinical rhythmic electrographic dischargestraumatic brain injury

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Area of Science:

  • Neurology
  • Neurocritical Care
  • Neurophysiology

Background:

  • Traumatic brain injury (TBI) poses risks for seizures and permanent neurological damage.
  • Identifying seizure incidence and risk factors post-TBI is crucial for patient outcomes.

Purpose of the Study:

  • To determine the incidence of seizures and continuous EEG (cEEG) abnormalities following TBI.
  • To identify risk factors associated with seizure development and electrographic abnormalities in TBI patients.

Main Methods:

  • Retrospective analysis of 245 adult patients with TBI undergoing cEEG within one week of admission.
  • Data extracted from trauma registry and electronic medical records at a Midwest Level 1 Trauma Center.

Main Results:

  • 35% of TBI patients exhibited seizures (12%) or high-risk electrographic patterns (23%).
  • 53% of seizures were only detected via cEEG.
  • Increased risk factors included age, prior epilepsy/TBI, hypertension, bleeding disorders, and dementia.

Conclusions:

  • The incidence of cEEG abnormalities in TBI patients is higher than previously reported.
  • Routine cEEG is recommended for critically ill TBI patients due to the high rate of missed seizures.
  • Early detection and management of TBI-related seizures can mitigate permanent neurological injury.