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Kidney Function in Factory Workers Exposed to Heat Stress: A 2-Year Follow-up Study
Fabiana B Nerbass1, Louise Moist, Marcos A Vieira
1From the Pró-Rim Foundation, Joinville, Santa Catarina, Brazil (Dr Nerbass, Dr Vieira); Division of Nephrology, Department of Medicine, Schulich School of Medicine, London, Ontario, Canada (Dr Moist); Kidney Clinical Research Unit, London Health Service Center, London, Ontario, Canada (Dr Moist); School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil (Dr Pecoits-Filho); Arbor Research Collaborative for Health, Ann Arbor, Michigan (Dr Pecoits-Filho).
Objectives:
The aims of the study are to re-evaluate kidney function in workers exposed and not exposed to heat stress after 2 years and to compare kidney function cross-shift using creatinine and cystatin C.
Methods:
Participants were workers from a metallurgical industry. The clinical and biochemical markers of hydration and kidney function were evaluated before and after a single shift in work.
Results:
We included 14 workers (6 in the heat group and 8 in the control group). The serum creatinine levels did not change during the follow-up period. Cross-shift, creatinine-based eGFR (estimated glomerular filtration rate) decreased, and cystatin C-based eGFR was maintained in the heat and control groups.
Conclusions:
Workers exposed to heat stress maintained their kidney function after a 2-year follow-up. Cystatin C is a better kidney function marker than creatinine for cross-shift assessments in this setting.
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