Effect of sedation using Ketamine for primary closure of pediatric facial laceration
Related Experiment Video
Updated: Sep 1, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Ju Ho Lee1, Sang Seok Woo, Se Ho Shin
1Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
Insights
Ketamine sedation is a safe and effective option for pediatric laceration repairs in the emergency room, improving procedure accuracy and parental satisfaction. This approach is recommended for more active use in clinical practice.
Area of Science:
- Emergency Medicine
- Pediatric Surgery
- Anesthesiology
Background:
- Pediatric lacerations often require sedation for suture procedures due to patient anxiety and pain.
- Existing shallow sedation methods are frequently insufficient, increasing the need for deeper sedation options.
Purpose of the Study:
- To evaluate the safety and efficacy of ketamine sedation for pediatric laceration repairs in the emergency room.
- To compare outcomes between ketamine sedation and local anesthesia in young children.
Main Methods:
- A study involving 106 pediatric patients (3 months to 5 years) with lacerations.
- 54 patients received intravenous ketamine (1.5-2.0 mg/kg) sedation; 52 control patients underwent procedures under local anesthesia.
- Vital signs, procedure times, and awakening were monitored.
Main Results:
- No statistically significant difference in total procedure time between the ketamine and non-sedation groups.
- Ketamine sedation facilitated accurate procedures and was associated with positive parental satisfaction.
- No adverse events were reported, indicating a safe profile for ketamine use.
Conclusions:
- Ketamine sedation is a safe and effective method for managing pediatric lacerations in the emergency setting.
- It aids in achieving accurate procedures, potentially minimizing scarring, and enhancing patient and parental experience.
- The study supports the more active utilization of ketamine for pediatric procedural sedation.
Abstract:
Pediatric lacerations are frequently encountered by plastic surgeons in the emergency room. Since pediatric patients cannot cooperate due to the anxiety and pain occurring during the suture procedure, sedation is induced. Since commonly used drugs inducing shallow sedation such as chloral hydrates are insufficient to perform procedures, the need or deep sedation has been increased. In our experience, inducing sedation with ketamine is safe and allows for accurate procedures. A total of 106 pediatric patients aged between 3 months to 5 years who visited the emergency room between August 2020 and January 2021 were included in this study. Of the 106 patients, 54 were sedated using ketamine, and the remaining 52 patients who did not cooperate were operated under local anesthesia, and these were set as the control group. The patients were intravenously injected with ketamine 1.5-2.0 mg/kg ketamine while monitoring the blood oxygen saturation, end-tidal CO2, and other vital signs. The patients were discharged as a complete awakening was confirmed by physicians. The number of patients who received sedation induced by ketamine was 54 and the number of patients who underwent the procedure without sedation was 52. The mean induction time of a single injection was 35.3 ± 11.3 minutes, and that of additional injection was 253.5 ± 54.1 minute. The total procedure time of the ketamine group was 20.3 ± 11.85 minutes, and that of the nonketamine group was 19.31 ± 10.50 minutes (P = .454). No statistically significant differences were found between the 2 groups. The need for sedation during the suture procedure in an emergenc9y room has been arising not only for reducing pain and anxiety, but also for safe and accurate procedures and scar minimization. Based on the parental satisfaction and the safety of the procedure, using ketamine is more effective than other drugs and should be used more actively.
More Related Videos
Related Concept Videos
Parenteral Anesthetics: Overview
Stages of General Anesthesia
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Inhalational Anesthetics: Overview
Local Anesthetics: Clinical Application as Spinal Anesthesia

