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Updated: Sep 1, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Lupus Erythematosus Tumidus Clinical Characteristics and Treatment: A Retrospective Review of 25 Patients
Adrian Pona1, Jesus Alberto Cardenas-de la Garza1, Alexa Broderick1
1Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina. Drs. Pona, Cardenas-de la Garza, Broderick, and Bowers are from the Center for Dermatology Research. Drs. Sanguenza and Niehuas also are from the Department of Dermatology. Dr. Pona also is from the Department of Internal Medicine, Vidant Medical Center/East Carolina University, Greenville, North Carolina. Dr. Cardenas-de la Garza also is from the Department of Dermatology, Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José E. González, Monterrey, México.
Abstract:
Lupus erythematosus tumidus (LET) is a rare photosensitive der-matosis that was considered a subtype of chronic cutaneous lupus erythematosus (CLE); however, its clinical course and favorable prognosis led to its reclassification into another category called intermittent CLE. Although known for more than 100 years, LET's association with systemic lupus erythematosus (SLE), autoantibody profile, and disease prognosis is not well characterized. The purpose of this study was to describe the demographics, clinical characteristics, autoantibody profile, comorbidities, and treatment of LET.
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