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Updated: Sep 1, 2025
Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
Published on: October 20, 2019
Complementary tool in diagnosis of hydatidiform mole: Review
Gabriela Marini Laviola1, Andreza Scapinello Fortini1, Débora Salles1
1Department of Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Botucatu Street, 740 - Vila Clementino, São Paulo, SP, Brazil; Laboratory of Molecular and Experimental Pathology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Pedro de Toledo Street, 781, 5º floor - Vila Clementino, São Paulo, SP, Brazil.
Abstract:
Hydatidiform mole is an abnormal pregnancy in which two copies of paternal genetic material are present. Molar gestation is divided into complete and partial hydatidiform moles. Clinical, morphological, and cytogenetic characteristics are usually sufficient to distinguish them, but and the rare cases that are necessary to know the paternal origin to establish the diagnosis and segment? Mutations in the Gene for Factor V Leiden and G20210A prothrombin polymorphism in women with recurrent spontaneous abortion: a retrospective study in a Brazilian population.
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