Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anterior sacral meningocele with S1 root incarceration: Marfan syndrome and its surgical management. Illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Impact of Procedural-Imaging Configurations on Radiation Dose During Endovascular Flow Diverter Treatment for Intracranial Aneurysms: A Comparison Between Hybrid Operating Room and Neuroangiography Suite.

Biomedicines·2026
Same author

The effectiveness of indirect revascularization on haemorrhagic moyamoya disease and the activities that trigger intracranial haemorrhage: a comprehensive study.

British journal of neurosurgery·2026
Same author

Cortical disinhibition in peripheral neuropathy unveiled by exploratory analysis of spectral alterations in contact heat-evoked potential.

Pain·2026
Same author

Divergent Small Vessel Disease Burden in Warfarin-Associated and Direct Oral Anticoagulant-Associated Intracerebral Hemorrhage.

Journal of stroke·2026
Same author

Genotype and subependymal lesion burden influence volumetric response to everolimus in tuberous sclerosis complex-associated subependymal giant cell astrocytoma: A 10-year real-world study.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Related Experiment Video

Updated: Sep 1, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.8K

A Proposed Algorithm for Managing Cerebral Proliferative Angiopathy.

Yu-Ning Chen1, Chung-Wei Lee2, Furen Xiao3

  • 1Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu City, Taiwan.

World Neurosurgery
|August 12, 2022
PubMed
Summary
This summary is machine-generated.

Cerebral proliferative angiopathy (CPA) is rare, with no standard treatment. Multi-modal therapy, combining approaches like revascularization and radiosurgery, is crucial for managing CPA effectively.

Keywords:
AlgorithmCerebral proliferative angiopathyEndovascular interventionIndirect revascularizationManagementRadiotherapy

More Related Videos

Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

11.9K
A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

2.8K

Related Experiment Videos

Last Updated: Sep 1, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.8K
Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

11.9K
A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

2.8K

Area of Science:

  • Neurology
  • Vascular Neurology
  • Interventional Neurology

Background:

  • Cerebral proliferative angiopathy (CPA) is a rare cerebrovascular disorder characterized by a large nidus, diffuse angiogenesis, and interspersed normal brain tissue.
  • Current treatment options including conservative management, endovascular intervention, indirect revascularization, and radiotherapy lack standardization, with some cases progressing despite intervention.
  • The absence of a defined treatment protocol necessitates further investigation into optimal management strategies for CPA.

Approach:

  • A systematic literature review adhering to PRISMA guidelines was conducted to analyze existing data on CPA management.
  • A case of a 6-year-old boy with left hemispheric CPA successfully treated with a multi-modal approach is presented.
  • The study proposes a management algorithm for CPA based on the literature review and the presented case.

Key Points:

  • A review of 23 articles identified 74 CPA cases, with 33 treated using single modalities (endovascular, revascularization, radiotherapy), showing variable outcomes including deterioration and mortality.
  • The presented case involved indirect revascularization followed by stereotactic radiosurgery for arteriovenous shunts, resulting in significant improvement over 4 years.
  • Successful outcomes included collateral formation, enhanced perfusion, CPA shrinkage, and symptom relief, highlighting the potential of combined therapeutic strategies.

Conclusions:

  • Multi-modal treatment is essential for the majority of Cerebral Proliferative Angiopathy cases.
  • The proposed management algorithm aims to guide clinicians in developing effective treatment strategies for CPA.
  • Further research and case reporting are vital to refine CPA treatment protocols and improve patient outcomes.