Related Experiment Video
Updated: Sep 1, 2025

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
Published on: June 16, 2011
Phylogenetic analysis of torque teno virus in Romania: possible evidence of distinct geographical distribution
Sonia Spandole-Dinu1,2, Dănuţ Cimponeriu3, Ileana Stoica1
1Department of Genetics, University of Bucharest, Intrarea Portocalelor 1-3, 060101, Bucharest, Romania.
Abstract:
Torque teno virus (TTV) is highly prevalent, but little is known about its circulation in humans. Here, we investigated the geographical distribution and phylogeny of TTV in Romania. A fragment of TTV untranslated region B was sequenced in samples from volunteers across the country. Additional sequences from dialyzed patients were also included in the study. Phylogenetic analysis showed that more than 80% of Romanian sequences clustered with isolates assigned to the species Torque teno virus 1 and Torque teno virus 3 (former genogroup 1), and this analysis discriminated between isolates from the North-East and West regions. Further studies assessing the pathogenic potential of TTV isolates should employ analysis based on genomic regions with phylogenetic resolution below the species level.
More Related Videos
08:56Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
Published on: July 27, 2018
08:10Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
Published on: May 2, 2019
Related Concept Videos
Viruses with RNA Genomes
Retroviruses
Viruses of Archaea
Non-LTR Retrotransposons
Size and Structure of Viral Genomes
Retrovirus Life Cycles