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X-ray Imaging

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...

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Updated: Sep 1, 2025

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

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Multispectral Large-Panel X-ray Imaging Enabled by Stacked Metal Halide Scintillators.

Peng Ran¹, Lurong Yang¹, Tingming Jiang¹

¹State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang, 310027, China.

Advanced Materials (Deerfield Beach, Fla.)

|August 13, 2022

Summary

This study introduces a new method for multispectral X-ray imaging using stacked scintillators. This technique enhances detail visibility in medical imaging by capturing spectral information lost in conventional X-ray systems.

Keywords:

metal halides multispectral X-ray imaging scintillators

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Area of Science:

Medical Imaging
Materials Science
Physics

Background:

Conventional X-ray imaging integrates photon energies, losing crucial spectral information.
Photon-counting detectors can distinguish X-ray spectra but are difficult for large-area flat-panel X-ray imaging (FPXI).

Purpose of the Study:

To develop a cost-effective method for multispectral FPXI.
To enable X-ray energy discrimination using stacked scintillators in a single exposure.

Main Methods:

Designed and fabricated multilayer stacked scintillators with varying X-ray absorption and emission spectra.
Utilized emerging metal halides in a scalable solution process.
Employed a color or multispectral visible-light camera to detect scintillator emissions.

Main Results:

Demonstrated proof-of-concept multispectral (multi-energy) FPXI.
Achieved clear dual-energy imaging of a "bone-muscle" model, revealing previously invisible details.
Developed a prototype FPXI with four energy channels by stacking four specifically designed scintillator layers.

Conclusions:

The stacked multilayer scintillator approach provides a facile and effective strategy for large-area multispectral X-ray imaging.
This method is extendable to hyperspectral X-ray imaging applications.
The technique overcomes limitations of conventional energy-integration imaging.