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Updated: Sep 1, 2025

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
Published on: September 13, 2020
Thoracic outlet syndrome: a review.
Eric J Panther1, Christian D Reintgen2, Robert J Cueto1
1College of Medicine, University of Florida, Gainesville, FL, USA.
Thoracic outlet syndrome (TOS) involves neurovascular compression in the thoracic outlet, causing arm symptoms. This review guides clinicians on diagnosing and treating TOS, focusing on vascular and verifiable neurogenic forms.
Area of Science:
- Vascular Surgery
- Neurology
- Orthopedics
Background:
- Thoracic outlet syndrome (TOS) is a rare condition caused by neurovascular compression.
- It presents with diverse symptoms including arm pain, swelling, fatigue, paresthesias, weakness, and hand discoloration.
- TOS is classified as neurogenic, arterial, or venous based on the compressed structure.
Purpose of the Study:
- To review diagnostic tests and treatment options for TOS.
- To guide clinicians in recognizing and treating vascular TOS.
- To focus on objectively verifiable forms of neurogenic TOS.
Main Methods:
- Review of diagnostic approaches including history, physical examination maneuvers, and imaging.
- Discussion of non-surgical treatments: anti-inflammatory medication, weight loss, physical therapy, and botulinum toxin injections.
- Overview of common surgical treatments: brachial plexus decompression, neurolysis, and scalenotomy with or without first rib resection.
Main Results:
- Diagnosis requires evidence of a physical anomaly, not just symptoms.
- Congenital abnormalities like cervical ribs can cause TOS.
- Nonsurgical and surgical treatment options are available, with specific postoperative rehabilitation protocols.
Conclusions:
- Accurate diagnosis of TOS relies on identifying a correctable physical anomaly.
- Effective management involves a combination of diagnostic tools and tailored treatment strategies.
- This review aims to improve the recognition and treatment of TOS, particularly vascular and verifiable neurogenic presentations.
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