Components of language processing and their long-term and working memory storage in the brain

There is a consensus that the temporal lobes are involved in representing various types of information critical for language processing, including phonological (i.e., speech sound), semantic (meaning), and orthographic (spelling) representations. An important question is whether the same regions that represent our long-term knowledge of phonology, semantics, and orthography are used to support the maintenance of these types of information in working memory (WM) (for instance, maintaining semantic information during sentence comprehension), or whether regions outside the temporal lobes provide the neural basis for WM maintenance in these domains. This review focuses on the issue of whether temporal lobe regions support WM for phonological information, with a brief discussion of related findings in the semantic and orthographic domains. Across all three domains, evidence from lesion-symptom mapping and functional neuroimaging indicates that parietal or frontal regions are critical for supporting WM, with different regions supporting WM in the three domains. The distinct regions in different domains argue against these regions as playing a general attentional role. The findings imply an interaction between the temporal lobe regions housing the long-term memory representations in these domains and the frontal and parietal regions needed to maintain these representations over time.