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Related Experiment Video

Updated: Sep 1, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
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Pelvic Radiation Disease.

Tarik Sammour1, Arman A Kahokehr2

  • 1Department of Colorectal Surgery, University of Adelaide, Royal Adelaide Hospital, Wayfinding, Adelaide, Australia.

Clinics in Colon and Rectal Surgery
|August 15, 2022
PubMed
Summary

Pelvic radiation therapy for cancer can cause severe side effects affecting nearby organs. Managing these pelvic radiation disease complications requires expert, multidisciplinary care to improve patient quality of life.

Keywords:
osteonecrosispelvic radiationradiation proctitisradiotherapyrecto-urethral fistula

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Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Complications

Background:

  • Pelvic radiation therapy is a common treatment for pelvic organ cancers.
  • While effective, it poses risks of significant toxicity and adverse events.
  • Understanding and managing these complications is crucial for patient care.

Purpose of the Study:

  • To review the spectrum of complications associated with pelvic radiation.
  • To highlight the challenges in diagnosis and management of pelvic radiation disease.
  • To emphasize the need for multidisciplinary input in mitigating adverse events.

Main Methods:

  • Literature review of pelvic radiation complications.
  • Classification and grading of adverse events based on consensus criteria.
  • Discussion of common manifestations and diagnostic challenges.

Main Results:

  • Pelvic radiation disease affects primary and adjacent organs and soft tissues.
  • Common complications include proctitis, cystitis, fistulas, ureteric strictures, and bone involvement.
  • Complication severity is dependent on radiation modality, dose, and area treated.

Conclusions:

  • Pelvic radiation toxicity can be severe and long-lasting, often misdiagnosed.
  • Effective management requires specialized, multidisciplinary teams.
  • Strategies to minimize impact and improve quality of life are essential.