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Updated: Sep 1, 2025

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Internalized-stigma and dissociative experiences in bipolar disorder.
Renato de Filippis1, Giulia Menculini2, Martina D'Angelo1
1Psychiatry Unit, Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Self-stigma is linked to dissociative symptoms in bipolar disorder (BD), negatively impacting quality of life. Early identification of patients with a history of abuse and high self-stigma is crucial for personalized treatment.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Dissociative symptoms are increasingly recognized in bipolar disorder (BD).
- Self-stigma exacerbates BD impairment, affecting treatment adherence and help-seeking behaviors.
- Overlapping features of internalized stigma and dissociation suggest a potential common pathway in BD.
Purpose of the Study:
- To investigate the relationship between dissociative symptoms and self-stigma in adult patients with bipolar disorder.
- To explore how these factors influence the quality of life in individuals with BD.
Main Methods:
- A cross-sectional study involving 120 clinically stable adult BD outpatients.
- Participants completed the Internalized Stigma of Mental Illness (ISMI) and Dissociative Experiences Scale-II (DES-II).
- The Manchester Short Assessment of Quality of Life (MANSA) was used to assess quality of life.
Main Results:
- Dissociative Experiences Scale (DES) scores significantly correlated with the Internalized Stigma of Mental Illness (ISMI) total score.
- Specific dissociative symptoms were associated with alienation and stereotype dimensions of self-stigma.
- Higher DES scores were significantly linked to lower quality of life as measured by MANSA.
Conclusions:
- This study provides evidence for an association between self-stigma and dissociative symptoms in bipolar disorder.
- These factors collectively reduce the overall quality of life for BD patients.
- Identifying patients with a history of abuse and high self-stigma is vital for tailored treatment strategies.
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