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Combined Mohs Micrographic Surgery in a Collision Tumor
Rafael A Montealegre1, Juan C Barrera1
1Dermatology, Instituto Nacional de Cancerología, Bogota, COL.
Cureus
|August 15, 2022
Summary
A rare collision tumor of basal cell carcinoma and melanoma in situ in a 73-year-old male was successfully treated with Mohs surgery. This technique, combining frozen and paraffin sections, achieved complete tumor removal and ear preservation.
Area of Science:
- Dermatology
- Surgical Oncology
- Pathology
Background:
- Collision tumors, where two distinct malignancies coexist in the same site, present unique diagnostic and therapeutic challenges.
- Basal cell carcinoma (BCC) and melanoma are common skin cancers, but their simultaneous occurrence as a collision tumor is infrequent.
- The management of such complex cases requires precise surgical techniques to ensure complete eradication and minimize recurrence.
Observation:
- A 73-year-old male presented with a collision tumor in the right ear, comprising both basal cell carcinoma and melanoma in situ.
- The patient underwent Mohs micrographic surgery, a specialized technique for removing skin cancer.
- The surgery involved a combination of paraffin-embedded and frozen tissue sections for accurate margin assessment.
Findings:
- Multiple surgical stages were necessary to achieve clear, tumor-free margins, indicating the complexity of the tumor.
- The surgical defect was successfully reconstructed by the plastic surgery team, preserving the anatomical structure of the ear.
- The combined use of paraffin-embedded and frozen sections proved effective in managing this specific collision tumor.
Implications:
- The successful application of Mohs micrographic surgery highlights its efficacy in treating complex skin cancer presentations.
- Combining paraffin-embedded and frozen section techniques offers a valuable approach for diagnosing and treating collision tumors of the skin.
- This case underscores the importance of tailored surgical strategies for preserving function and form in oncologic reconstruction.

