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Updated: Sep 1, 2025

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Acute Kidney Injury in COVID-19: Clinical Profile and Outcome
Jyoti Bansode1, Salman Ali Sayed1, Shakir Ahmad1
1Department of Nephrology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.
Acute kidney injury (AKI) in COVID-19 patients is common, with a high mortality rate. Among survivors, nearly half progress to chronic kidney disease (CKD), highlighting the long-term renal impact of this infection.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) is a serious complication of COVID-19.
- Limited data exists on the long-term renal outcomes for COVID-19 patients who develop AKI.
Purpose of the Study:
- To investigate the incidence, clinical characteristics, and outcomes of AKI in COVID-19 patients.
- To assess the rate of renal recovery and progression to chronic kidney disease (CKD) at 3-month follow-up.
Main Methods:
- Prospective enrollment of COVID-19 patients with AKI.
- Analysis of clinical data, laboratory results, and renal function at discharge and 3 months post-discharge.
Main Results:
- AKI incidence was 3.16% among COVID-19 patients.
- The 3-month mortality rate was 55.85%.
- Among survivors, 49% progressed to CKD, while 43% recovered renal function.
Conclusions:
- COVID-19 associated AKI carries a high mortality risk.
- Survivors face a significant risk of progressing to CKD, underscoring the need for renal monitoring.
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