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Early Real-World Physician Experience with an Intracanalicular Dexamethasone Insert
Cynthia Matossian1, John D Stephens2, Michelle K Rhee3
1CM Associates, LLC, New Hope, PA, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|August 15, 2022
Summary
Physicians report high satisfaction and improved patient compliance with the new intracanalicular dexamethasone insert (DEX) after cataract surgery. This innovative therapy offers a promising alternative for managing post-surgical inflammation and pain.
Area of Science:
- Ophthalmology
- Ophthalmic Surgery
- Pharmacology
Background:
- Post-cataract surgery inflammation and pain are common concerns.
- Traditional steroid eye drops require frequent administration and adherence can be challenging.
Purpose of the Study:
- To evaluate early physician experiences with an intracanalicular dexamethasone insert (DEX) in cataract surgery patients.
- To assess the clinical impact and physician adoption of this novel therapy.
Main Methods:
- A Phase 4, cross-sectional survey study involving 23 US sites.
- Three sequential online surveys administered to physicians with early experience using DEX in cataract surgery patients.
- Descriptive statistics were used to analyze survey responses.
Main Results:
- Forty-two physicians completed the surveys.
- Physicians reported high satisfaction (92%) with DEX and noted improved patient compliance (100%).
- A majority (62.5%) preferred DEX over traditional steroid eyedrops for managing post-surgical inflammation and pain.
Conclusions:
- The intracanalicular dexamethasone insert (DEX) demonstrates a rapid learning curve and effective clinical integration.
- Physicians reported a positive early experience, including ease of administration and high satisfaction.
- DEX shows potential as a preferred treatment for post-cataract surgery inflammation and pain, offering a convenient, hands-free, preservative-free steroid delivery.
