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Fungal Group Zygomycota01:29

Fungal Group Zygomycota

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Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
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COVID-19 Associated Mucormycosis (CAM): A Single Hospital-Based Study.

Manjunath M Vijapur1, Vasanth Kattimani2, V K Varsha3

  • 1Department of Oral and Maxillofacial Surgery, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.

Journal of Oral and Maxillofacial Pathology : JOMFP
|August 15, 2022
PubMed
Summary

COVID-19 associated Mucormycosis (CAM) is a significant challenge, particularly in India. This study found Rhino orbital type common, with palatal issues prevalent, and highlighted Diabetes Mellitus as a key comorbidity requiring monitoring.

Keywords:
COVID-19diabetesmucormycosis

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Oral and Maxillofacial Surgery

Background:

  • Mucormycosis presents a significant challenge for healthcare professionals managing Coronavirus Disease 2019 (COVID-19) patients, especially in India.
  • Understanding the behavior of COVID-19 associated Mucormycosis (CAM) is crucial for developing standardized treatment protocols and reducing mortality.

Purpose of the Study:

  • To assess Mucormycosis types in COVID-19 patients.
  • To compare Mucormycosis types with clinical, radiological, and hematological parameters.
  • To evaluate treatment and surgical management strategies for CAM.

Main Methods:

  • Retrospective, observational study of 60 CAM cases.
  • Data collected from the Department of Oral and Maxillofacial Surgery.
  • Statistical analysis including Chi-Square, Spearman's Correlation, and Linear Regression.

Main Results:

  • Approximately 50% of patients presented with the Rhino orbital type of Mucormycosis.
  • Palatal discoloration and erosion were the most frequent oral manifestations in Sinus and Rhino orbital types (P=0.00).
  • A significant association was observed between Diabetes Mellitus type and Mucormycosis (P=0.29).

Conclusions:

  • Diabetes Mellitus (DM) is the most frequent comorbidity in CAM patients.
  • Close monitoring of DM in COVID-19 patients is mandatory for successful treatment outcomes.
  • Understanding underlying comorbidities is essential for managing CAM effectively.