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Multiple myeloma with t(11;14): unique biology and evolving landscape

Susan Bal1, Shaji K Kumar2, Rafael Fonseca3

  • 1Department of Medicine, Division of Hematology Oncology, O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham Birmingham, AL, USA.

American Journal of Cancer Research
|August 15, 2022
PubMed
Summary

Multiple myeloma with the t(11;14) translocation is a distinct subtype characterized by specific biological features and presents a targeted therapy opportunity with BCL-2 inhibition. Further research is needed to clarify its prognostic significance.

Keywords:
BCL-2Multiple myelomaprognosist(11;14)targeted therapy

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