Life beyond alpha-thalassaemia: We are moving forward
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Updated: Sep 1, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
1Hemoglobinopathies Unit, Hematology Department, S. Eugenio Hospital (ASL Roma 2), Rome, Italy.
Abstract:
In the not so distant past, pregnancy in thalassaemia patients was considered a very high risk and often not recommended. The results regarding alpha-thalassaemia and in particular haemoglobin H disease by Srimeuniwai and colleagues are very encouraging. Nowadays thalassaemic women not only become pregnant, but maternal outcome is not decreased compared to controls. Commentary on: Ake-sittipaisarn, et al. Outcomes of pregnancies complicated by haemoglobin H-Constant Spring and deletional haemoglobin H disease: A retrospective cohort study. Br J Haematol 2022;199:122-129.
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