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Updated: Sep 1, 2025

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
Chemotherapy-Induced Toxicities: An Imaging Primer.
Nikhil S Patil1, Natasha Larocque2, Christian B van der Pol3
1Michael DeGroote School of Medicine, 62703McMaster University, Hamilton, ON, Canada.
The COVID-19 pandemic delayed cancer treatments, leading to more chemotherapy toxicities. This review aids radiologists in identifying diverse imaging findings of these treatment side effects.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- The COVID-19 pandemic disrupted cancer care delivery in Canada.
- Increased incidence of chemotherapy-induced toxicities is anticipated as cancer services resume.
- Radiologists need updated knowledge on diverse imaging manifestations of these toxicities.
Purpose of the Study:
- To provide a comprehensive review of imaging findings associated with chemotherapy-induced toxicities.
- To serve as a unified resource for general radiologists.
- To enhance the recognition and diagnosis of treatment-related complications in cancer patients.
Main Methods:
- Literature review of imaging findings in chemotherapy-induced toxicities.
- Synthesis of information from various imaging modalities (e.g., CT, MRI, Ultrasound).
- Categorization of toxicities by organ system affected.
Main Results:
- Chemotherapy-induced toxicities present with a wide spectrum of imaging appearances.
- Multiple organ systems can be affected, requiring broad radiological knowledge.
- Characteristic and atypical imaging patterns are discussed for various agents.
Conclusions:
- Accurate interpretation of imaging is crucial for managing chemotherapy-induced toxicities.
- This review offers a valuable reference for radiologists encountering these cases.
- Timely diagnosis aids in optimizing patient care and treatment strategies.
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