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Diminishing hERG inhibitory activity of aminopiperidine-naphthyridine linked NBTI antibacterials by structural and

Maja Kokot1, Matjaž Weiss2, Irena Zdovc3

  • 1Theory Department, Laboratory for Cheminformatics, National Institute of Chemistry, Hajdrihova 19, 1001 Ljubljana, Slovenia; The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia.

Bioorganic Chemistry
|August 15, 2022
PubMed

Keywords:
Bacterial type II topoisomerasesDNA gyraseNBTIsTertiary aminehERGtopoisomerase IV

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