Leptomeningeal Carcinomatosis: A Case Report and Literature Review

Leptomeningeal carcinomatosis (LC) is a rare complication of malignant tumors that involves metastasis to the meninges surrounding the brain and/or spinal cord. The incidence of LC appears to be increasing, which has been attributed to increased survival times of cancer patients and increased diagnostic sensitivity. In this case, we discuss a patient with a history of colon cancer and lung cancer who was admitted with multiple cranial nerve palsies and sensory deficits. An MRI with contrast showed multiple enhancing intracranial lesions with leptomeningeal enhancement. Neurology and neurosurgery were consulted, and the patient was ultimately discharged to hospice.