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Musculoskeletal symptoms in patients with long COVID: A cross-sectional study on Iranian patients

Mohaddeseh Azadvari1,2, Afarin Haghparast3, Amin Nakhostin-Ansari3,4

  • 1Department of Physical Medicine and Rehabilitation, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Heliyon
|August 16, 2022
PubMed

Insights

Most COVID-19 survivors experience persistent musculoskeletal symptoms like fatigue and myalgia. High BMI and hospitalization increase the risk, suggesting targeted interventions for better recovery.

Area of Science:

  • Medical Research
  • Infectious Diseases
  • Rehabilitation Medicine

Background:

  • Emerging evidence indicates persistent symptoms in many Corona Virus Disease of 2019 (COVID-19) patients post-acute infection.
  • Musculoskeletal (MSK) symptoms are increasingly recognized as a significant post-COVID-19 complication.

Purpose of the Study:

  • To determine the prevalence of musculoskeletal symptoms following the acute phase of COVID-19.
  • To identify factors associated with the occurrence of these persistent symptoms.

Main Methods:

  • A cross-sectional online survey was conducted between January 2021 and April 2021.
  • Data collected included demographics, acute COVID-19 course, and post-recovery MSK symptoms.
  • Statistical analysis evaluated associations between patient characteristics, COVID-19 history, and MSK symptom prevalence.

Main Results:

  • 239 COVID-19 survivors participated (30.1% male, 69.9% female; mean age 37.96 years).
  • A high prevalence of post-COVID-19 MSK symptoms was observed, with 98.74% reporting at least one symptom.
  • Fatigue (91.2%), myalgia, headache, and low back pain were the most common symptoms. Higher BMI, hospitalization, and ICU admission correlated with increased MSK symptom risk.

Conclusions:

  • Persistent musculoskeletal symptoms are highly prevalent in COVID-19 survivors.
  • Modifiable risk factors like Body Mass Index (BMI) present opportunities for targeted interventions.
  • Addressing these symptoms can potentially reduce the long-term burden of COVID-19 on survivors.
Abstract

Keywords:
COVID-19Long-COVIDMusculoskeletal symptomsPost-acute COVID19 syndromeSARS-CoV-2

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